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A zymogen is an inactive enzyme pre-cursor. A zymogen requires a biochemical change, such as a hydrolysis reaction revealing the active site, for it to become an active enzyme.

Examples of zymogens are the pancreatic trypsinogen which becomes trypsin and chymotrypsinogen which becomes chymotrypsin.

The proteasome is also a zymogen. The catalytic beta subunits are cleaved to reveal the reactive threonine.

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ZymogenA zymogen is an inactive enzyme pre-cursor. A zymogen requires a biochemical change, such as a hydrolysis reaction revealing the active site, for it to become an active enzyme. Examples of zymogens are the pancreatic trypsinogen which becomes trypsin and

ZymoGeneticsZymoGenetics is a biotechnology/ pharmaceutical company based in Seattle, Washington involved in the development of therapeutic proteins. The company was founded in 1981 by Professors Earl W. Davie and Benjamin D. Hall of the University of Washington and

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