| • Science | • People | • Locations | • Timeline |
While it acts on the BZ2 receptor and is a short-acting hypnotic agent, it is not a benzodiazepine, but a cyclopyrrolone derivative, belonging to a novel chemical class which is structurally unrelated to existing hypnotics.
The side-effects most commonly seen in clinical trials is taste alteration (bitter taste).
Gastrointestinal: bitter taste, dry mouth.
Nervous System: drowsiness, headaches, fatigue.
Gastrointestinal: heartburn, constipation, diarrhoea, nausea, coated tongue, bad breath, anorexia or increased appetite, vomiting, epigastric pain s, dyspepsia .
Cardiovascular: palpitationA palpitation is an abnormal, rapid beating of the heart, brought on by overexertion, disease or drugs. It can also refer to a shaking motion. Nearly everyone experiences a very occasional awareness of their own heart beating, but when it occurs frequentls in elderly patients.
Skin: urticariaUrticaria or Hives is a relatively common form of allergic reaction. Hives are a series of raised red skin welts ranging upwards from 5 mm (about a 1/4 inch) in diameter and often have a pale border. They are caused by direct contact with an allergenic su, tingling.
Miscellaneous: blurred vision, micturition, mild to moderate increases in serum transaminas es and/or alkaline phosphataseA phosphatase is an enzyme that hydrolyses phosphomonoesters. This action is directly opposite to that of kinases, which attach phosphate groups to their substrates. The presence or absence of the phosphate group on proteins, especially enzymes, is known have been reported very rarely.
Reproductive: impotence, ejaculation failure.
Nervous system: agitation, anxiety, loss of memory including retrograde amnesia, confusion, dizziness, weakness, somnolence, asthenia, feeling of drunkenness, euphoria, depression, coordination abnormality, hypotonia, speech disorder, hallucinations (auditory and visual), behavioural disorders, aggression, tremor, rebound insomnia, nightmares.