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Home > Sertraline


 

Sertraline hydrochloride (Zoloft®, Lustral®, Apo-Sertral®, Asentra®, Gladem®, Serlift®, Stimuloton®) is an orally administered antidepressant of the selective serotonin reuptake inhibitor (SSRI) type. Sertraline is used medically mainly to treat the symptoms of depression.

Sertraline is manufactured by Pfizer as small green 25 mg tablets, blue 50 mg tablets, or off-yellow 100 mg tablets. (In Australia it is available as white tablets in 25, 50 or 100mg doses.) It is used in dosages of between 25 mg and a maximum of 200 mg per day. It has also been prescribed for the treatment of obsessive-compulsive disorder, post-traumatic stress disorder, premenstrual dysphoric mood disorder, panic disorder, and social anxiety. It was first approved by the FDA in 1997.

It has a number of adverse effects including insomnia, asthenia, gastrointestinal complaints, tremours, confusion, and dizziness; it can induce mania or hypomania in around 0.5% of patients. One property of sertraline is that it appears to be also a minor inhibitor of dopamineDopamine is a neurotransmitter in the brain. As a member of the catecholamine family, dopamine is a precursor to epinephrine ( adrenaline) and norepinephrine ( noradrenaline) in the biosynthetic pathways for these neurotransmitters. Dopamine is synthesize reuptake. It is contraindicated in individuals taking MAOIs or undergoing electroconvulsive therapyElectroconvulsive therapy also known as electroshock or ECT is a controversial type of psychiatric shock therapy involving the induction of an artificial seizure in a patient by passing electricity through the brain. Researchers remain uncertain as to exa. In June of 2003, BritainThe word Britain is used to refer to the United Kingdom (UK): i. the United Kingdom of Great Britain and Northern Ireland (from 1927), the United Kingdom of Great Britain and Ireland ( 1801- 1927) or the United Kingdom of Great Britain ( 1707- 1801). banned the use of Zoloft for children under 18 after studies showed a link to increased suicide.

The complete chemical name for Sertraline hydrochloride is (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-nanphthalenamine hydrochloride, CAlternative meaning: Carbon (computing Carbon is a chemical element in the periodic table that has the symbol C and atomic number 6. An abundant nonmetallic, tetravalent element, carbon has several allotropic forms: diamonds (hardest known mineral). Bindi17 Hhydrogen helium H Li Full table General Name, Symbol, NumberHydrogen, H, 1 Chemical series nonmetals Group, Period, Block 1 (IA), 1 , s Density, Hardness 0. 0899 kg/m3, NA Appearance colorless Atomic properties Atomic weight 1. 00794 amu Atomic radius (ca17 NNitrogen is the chemical element in the periodic table that has the symbol N and atomic number 7. A common normally colorless, odorless, tasteless and mostly inert diatomic non-metal gas, nitrogen constitutes 78 percent of Earth's atmosphere and is a cons ClChlorine (from Gr. Chloros meaning "pale green"), is the chemical element with atomic number 17 and symbol Cl . It is a halogen, found in the periodic table in group 17. Chlorine gas is greenish yellow, is two and one half times as heavy as air, has an in2· HCl). It is an odorless, white, sparingly soluble crystalline solid with a molecular weight of 342.7.



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