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Home > Zinc finger


 

A zinc finger is part of a protein that can bind to DNA. Zinc finger domains typically consist of two β sheets, each carrying a cysteine residue, and an α helix carrying two histidine residues. The cysteine and histidine residues bind a zinc atom.

Many transcription factors (such as Zif268 ), regulatory proteins, and other proteins that interact with DNA, all contain zinc fingers.

These proteins possess amino acid sequences that combine with a zinc ion. They typically interact with the major and minor grooves along the double helix of DNA.

Protein structural motifs

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