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Sister, Sister is a 1982 TV movie based on a Maya Angelou story, starring Diahann Carroll, Irene Cara and Rosalind Cash as three sisters with moral and personal conflicts trying to maintain a household after the death of their father. (IMDb listing)
Sister, Sister is a 1987 thriller starring Eric Stoltz, Jennifer Jason Leigh, and Judith Ivey . The girls run a guesthouse in the Louisiana swamp, where the secrets of their dark past will eventually come to light. (IMDb listing)
Sister, Sister is a Disney Channel television series about two African American girls who have found out that they are twin sisters.
The show stars Tia and Tamera Mowry as the twins, and features occasional appearances by Brittany Murphy as their best friend. (IMDb listing)