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In the scientific study of genetics, quantative trait loci (QTL) are sets of genes at specific places ( loci, singular locus) in the genotype (the genetic information encoded in a species' DNA) which control a particular phenotype (specific aspect of the species' physical development). The different sets of genes which may appear in any one specific locus are called alleles. The set of different combination of alleles which appear at all the sites in the QTL control the final resulting expression of the trait in the phenotype.1 QTL mapping
QTL mapping is the statistical study of the alleles which occur in a locus and the phenotypes (physical forms or traits) that they produce. Because most traits of interest are governed by more than one gene, defining and studying the entire locus of genes related to a trait gives hope of understanding what effect the genotype of an individual might have in the real world.
Statistical analysis is required to prove that different genes interact with one another, and to determine whether they are producing a significant effect in the phenotype.
- To do: describe the biology behing the analysis, how the analysis is performed, and the reasons why it works.
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