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Flamel is supposed to have been the most accomplished of the European alchemists. It is claimed that he succeeded at the two magical goals of alchemy supposed to have been the chief aims of that pseudoscience: he made the Philosopher's Stone that turns lead into gold, and he and his wife Perenelle achieved immortality.

Flamel is supposed to have received a mysterious book from a stranger, full of qabalistic words in Greek and HebrewThe Modern Hebrew language is a Semitic language of the Afro-Asiatic language family. What makes it unique is that the original Bible, the Torah, by Orthodox Jews held to be recorded in the time of Moses 3,300 years ago, was written in Biblical Classical. Flamel made the understanding of this text of lost secrets his life's work, travelling to universities in AndalusiaAndalusia Andalucia in Spanish) is one of the seventeen autonomous communities that constitute Spain. Located in the south of the country, Andalusia is bounded on the north by Extremadura and Castile-La Mancha, on the east by Murcia, on the south by the M to consult with JewThe word Jew is used in a wide number of ways, but generally refers to either a follower of the Jewish faith, a child of a Jewish mother, or a member of the Jewish culture or ethnicity. This article discusses the term as describing an ethnic group; for aish and MuslimCairo Egypt Islm (In Arabic: , "submission (to God)"; In Persian and Urdu: ) is a monotheistic faith and the world's second-largest religion. Followers of Islam, known as Muslims believe that God (or, in Arabic, Allh revealed His Will to Muhammad (c. authorities. In SpainThe Kingdom of Spain is a country located in the southwest of Europe. It shares the Iberian Peninsula with Portugal, Gibraltar and Andorra. To the northeast, along the Pyrenees mountain range, it borders France and the tiny principality of Andorra. It inc, he met a mysterious master called Abraham the JewAbraham the Jew may refer to: # Abraham, ancestor of the Jews in the Book of Genesis; or # Abramelin, the pseudonymous author of a grimoire (a magical textbook). The person who instructed Nicholas Flamel in alchemy, and gave him an illuminated manuscript who taught him the art of understanding his manuscript.

After his return from Spain, Flamel was able to become rich: the knowledge that he gained during his travels made him a master of the alchemical art. Flamel became a philanthropistPhilanthropy involves the donation or granting of money to various worthy charitable causes. It is seen as a way to directly effect change in society without recourse to the bureaucratic mechanisms of government. Someone who practices philanthropy is know, endowing hospitals and churches with the proceeds from his alchemical work. He caused arcane alchemical signs to be written on a tombstone, which is preserved at the Musée de Cluny in Paris. His tomb is empty; some say it was sacked by people in search of his alchemical secrets. On the other hand, if he in fact achieved the secret of immortality, his empty tomb may have another explanation.

Nicholas Flamel's story is alluded to in J. K. Rowling's first Harry Potter book, Harry Potter and the Philosopher's Stone (or, Sorcerer's Stone). He is also mentioned as a Grand Master of the Priory of Sion in Dan Brown's The Da Vinci Code and the 1982 book Holy Blood, Holy Grail, and is mentioned on several occasions (chapters 20 and 44) in Victor Hugo's The Hunchback of Notre Dame.

Flamel had these mysterious alchemical symbols carved on his tomb in the Church of the Holy Innocents in Paris.