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A spinoff from Beverly Hills 90210 (though not featuring any permanent cast members crossing over), Melrose Place is an apartment block in the West Hollywood district of Los Angeles with young adults living in it. During the first season, the show was a relatively earnest serial drama focused on how young people come to Los Angeles to realize their dreams. As time went by, the show took a more sensational and soapish turn as more and more rich and powerful characters appeared and the focus was on their rivalry for power and money. The show is remembered fondly for its twist endings, miniskirts, and the many "vixens" who were regulars on the show, such as Heather Locklear, Marcia Cross, Courtney Thorne-Smith and Alyssa Milano.
Dr. Michael Mancini, played by Thomas Calabro, was the only original character that appeared during every season. Jane Andrews Mancini, played by Josie Bissett, took a brief hiatus but returned for the final season.
In the United States, the show appeared on the Fox network, and had runs around the world.