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In molecular biology, the insulin receptor is a transmembrane receptor that is activated by insulin. It belongs to the large class of tyrosine kinase receptors.

Two alpha subunits and two beta subunits make up the insulin receptor. The beta subunits pass through the cellular membrane and are linked by disulfide bonds.

The insulin receptor transports phosphate groups from ATP to proteins within a cell. This leads to an increase in glucose transporter molecules in the outer membrane of muscle cells and adipocytes, and therefore to an increase in the uptake of glucose from blood into muscle and adipose tissue.

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OMIM entry 147670

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Tyrosine kinase receptors

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Topics: Insulin Receptor, Insulin Pump, Insulin like Growth Factor...

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