Home > Glomerulus (kidney)

Glomerular endothelial cells are perforated by thousands of small 'cracks' known as "fenestrae". These 'cracks' allow water and small solutes to pass through, but not proteins and cells.

Blood is fed to the glomerulus through the afferent arteriole, and empties into the efferent arteriole. The difference in pressure in the arterioles results in the process of ultrafiltration where fluids and soluble materials in the blood are forced out of the capillaries and into the Bowman's capsule.

Fluids collected in the Bowman's capsule is known as glomerular filtrate, which eventually becomes urine after further processing along the nephron.