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Go-Nijo was the eldest son of the 91st Emperor Go-Uda. He belonged to the Daikakuji-to branch of the Imperial Family.
In 1286 he became a shinno by Imperial Proclamation. In 1296, he became Crown Prince to the Jimyoin-to Emperor Go-Fushimi, his second cousin.
On March 3, 1301, he became Emperor upon the abdication of Go-Fushimi. On September 10, 1308, he died of illness.
His father, the Go-Uda Emperor reigned as cloistered Emperor during his reign.
The succession dispute between the Daikakuji and Jimyoin branches of the Imperial Family continued during his reign. His grandfather, the retired Emperor Kameyama was said to have acted through the Bakufu to ensure Go-Nijo's enthronement.
| Preceded by: Go-Fushimi | Emperor of Japan | Succeeded by: Hanazono |