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He was the third son of Emperor Go-Yozei. His mother was the daughter of Konoe Sakihisa
On the third month, 27th day, Keicho 16 (1611), he became Emperor upon the abdication of his father, Emperor Go-Yozei. On the 4th month, 12th day, he performed a ceremony of gratitude for his enthronement.
When it was found out that his favorite court lady while he was a prince was an imperial princess, Tokugawa Hidetada threatened to cancel the engagement to his daughter, Tokugawa Kazuko. However, apologizing for his actions, Tokugawa Kazuko was welcomed into the Imperial court. In 1627, the Purple Clothes Incident occurred, Tokugawa Iemitsu's wet nurse, being without rank or title, visited the Imperial court. The Emperor, who was unable to retain influence in the face of the shogunate, abdicated in favor of his daughter, who became the Meisho Empress.
He passed away in 1680.
In the grounds of the Sokoku-ji in the Kamigyo Ward of Kyoto, Emperor Go-Mizunoo's teeth and hair are located, serving to enshrine him.
| Preceded by: Go-Yozei | Emperor of JapanThe following is a traditional list of emperors of Japan Empresses are listed in italic. indicates an emperor or empress who is not a direct patrilineal ancestor of the current emperor. Dates for the first 28, especially the first 16, are based on traditi | Succeeded by: Empress Meisho |