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The more important towns and villages along the course of the river are Sterzing-Vipiteno, Franzensfeste-Fortezza , Brixen-Bressanone, Klausen-Chiusa and Waidbruck-Ponte Gardena . Several smaller creeks flow into the Eisack, including the Ridnauner Bach , the Pflerscher Bach , the Pfitscher Bach , Rienz , the Villnösser Bach , the Grödner Bach , the Braibach (also known as Tierser Bach), the Eggentaler Bach and the Talfer flowing from the Sarntal .
The Eisack is used extensively for the production of electricity and is dammed near Franzensfeste, Klausen and Waidbruck.