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In 1873, Cantonalists took over the city of Cartagena, SpainFor other places of the same name, see Cartagena Cartagena is a seaport in southeast Spain on the Mediterranean Sea, in the autonomous community of Murcia. The coordinates of Cartagena are 37º36' N, 0º59' W . It is a walled town and has a fine harbor defe, a haven for the Spanish Navy, and declared the city independent.