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Bleomycin is an anti- cancer agent. It is a glycosylated linear nonribosomal peptide antibiotic produced by the bacterium Streptomyces verticillus. It acts by induction of DNA strand brakes and is used in the treatment of lymphomas, squamous cell carcinomas, and testicular cancer as well as pleurodesis. Its use is limited by the increased risk of pulmonary fibrosis . Other side-effects include fever, rash, hyperpigmentation and alopecia.
Chemotherapeutic agents
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