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Home > Behçet's disease


 

Behçet's disease (BD, or Behçet's syndrome) is a rare, multisystem disease with chronic inflammation of blood vessels (i.e. vasculitis). It is also known as Silk Road Disease.

1 History

Behçet's disease is named after Hulusi Behçet (1889-1948), the Turkish dermatologist and scientist who first recognized the syndrome in one of his patients in 1924 and reported his research on the disease in Journal of Skin and Veneral Diseases in 1936. The name (Morbus Behçet) was formally adopted at the International Congress of Dermatology in Geneva in September 1947.

Benedikt Adamandiades, a Greek ophthalmologist, reportedly described the disease six years before Behçet did. Nevertheless, only Greek scientists refer to the disease Adamantiades-Behçet's or even Adamantiades' disease.

2 Pathology

Behçet's disease is believed to be caused by an over-active immune system which, without any apparent infections, produces recurrent outbreaks of inflammation in small blood vessels. As a result, symptoms can occur anywhere in the body with a blood supply. Common symptoms include mouth ulcers, sore genitals and eyeThis article refers to the sight organ. See Eye (disambiguation) for other usages. human eye. Note that not all eyes have the same anatomy as a human eye. An eye is an organ that detects light. Different kinds of light-sensitive organ are found in a varie inflammation, and arthritisArthritis (from Greek arthro joint + itis inflammation) is a group of conditions that affect the health of the bone joints in the body. One in three adult Americans suffer from some form of arthritis and the disease affects about twice as many women as me in older patients, mostly painful but not life-threatening conditions. However, some patients may be unable to work because of the pain and the impaired vision and mobility. In some severe cases, uncontrolled inflammation may lead to blindnessBlindness can be defined physiologically as the condition of lacking sight. The definition as it applies to people thus legally classified is, however, more complex. The term "blindness" also applies to partial visual impairment: In North America and most, intestinal complicationsIn medicine ( gastroenterology), the term irritable bowel syndrome (IBS) refers to a group of functional bowel disorders which are fairly common and make up 20 50% of visits to a specialist. Features Symptoms of IBS are abdominal pain or discomfort associ, stroke, and even meningitisMeningitis is inflammation of the membranes ( meninges) covering the brain and the spinal cord. Although the most common causes are infection (either bacterial or viral), chemical agents and even tumor cells may cause meningitis. Encephalitis and brain ab, which can become fatal.

This disease usually first strikes patients in their 20s and 30s. Then, it becomes a lifelong disorder that proceeds in a series of remissionRemission is the state of absence of disease activity in patients with known chronic illness. It is commonly used to refer to absence of active cancer or inflammatory bowel disease. REMISSION ''n (lat. remittere): In spectrosopy, the term "remission" refes (periods of apparent good health, usually a few months) and exacerbations (periods of active disease and progression, can be a week to a month). Complete remission is rare.



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