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The novel was adapted for the stage by authors Jerome Lawrence and Robert E. Lee. The original Broadway production starred Rosalind Russell in the title role.

In 1958, a film based on the play was released. In addition to Russell, it starred Forrest Tucker, Coral Browne , Roger Smith, Peggy Cass and Jan Handzlik . The screenplay was adapted by Betty Comden and Adolph Green, and the movie was directed by Morton DaCosta .

It was nominated for Academy Awards for Best Actress in a Leading Role (Rosalind Russell), Best Actress in a Supporting Role (Peggy Cass), Best Art Direction-Set Decoration, Black-and-White or Color, Best Cinematography, Color, Best Film EditingThe Academy Award for Film Editing was first given for films issued in 1934. 1930s 1934 Eskimo Conrad A. Nervig Cleopatra Anne Bauchens One Night of Love Gene Milford 1935 A Midsummer Night's Dream Ralph Dawson David Copperfield Robert J. Kern The Informe and Best Picture.

A musical version, entitled MameFor the arcade emulator, see MAME. Mame is a Broadway musical. The plot revolves around eccentric Mame Dennis, whose madcap life is disrupted when her deceased brother's son Patrick is entrusted to her care. Rather than bow to convention, Mame introduces, opened on Broadway in 1966Events January January 1 In a coup, Colonel Jean-Bedel Bokassa ousts president David Dacko and takes over the Central African Republic. January 2 Strike of public transportation workers in New York City ends January 13 January 3 First Acid Test at the Fil.