Science  People  Locations  Timeline
Index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Home > Angioedema


 Contents
Angioedema ( BE: angiooedema), also known by its eponym Quincke's edema and the older term angioneurotic edema is the rapid swelling ( edema) of the skin, mucosa and submucosal tissues. If it proceeds rapidly, it can lead to airway obstruction and suffocation, and it should therefore be treated as a medical emergency.

Apart from the common form, mediated by allergy, it has been reported as a side-effect to some medications, specifically ACE inhibitors. Additionally, there is an inherited form termed hereditary angioedema (HAE) or hereditary angio-neurotic edema (HANE). It is due to C1-esterase inhibitor deficiency.

1 Signs and symptoms

The skin of the face (around the mouth) and the mucosa of the mouth, as well as the tongue, swell up over the period of minutes to an hour. Often, there has been recent exposure to an allergen (e.g. peanuts), and urticaria (hives) develop simultaneously. The swelling is itchAn itch ( Latin: pruritus is a sensation felt on an area of skin that makes a person or animal want to scratch it. Mechanism The central chemical in itch is histamine, a molecule released by mast cells in the skin. Histamine is the chemical that causes thy.

In severe cases, stridor of the airway occurs, with gasping inspiratory breath sounds and decreasing oxygenOxygen is the chemical element in the periodic table that has the symbol O and atomic number 8. The element is very common, found not only on Earth but throughout the universe. Molecular oxygen (O, often called free oxygen on Earth is thermodynamically un levels. IntubationIntubation being practiced on a dummy (conventional technique using a laryngoscope) In medicine, intubation is the placement of a tube into an external or internal orifice of the body. Although the term can refer to endoscopic procedures, it is most often and rapid treatment with adrenalin and antihistamineAn antihistamine is a chemical which serves to reduce or eliminate effects mediated by histamine, an endogenous chemical of the human body released during allergic reactions, at the histamine receptor. It can be administered locally (through the skin, noss is required in these situations.

In hereditary angioedema, there is often no direct identifyable cause, although mild traumaIn medicine, a trauma patient has suffered serious and life-threatening physical injury resulting in secondary complications such as shock, respiratory failure and death. Trauma patients require specialized care including surgery and often blood transfusi and other stimuli can cause attacks. Patients with this syndrome (also termed C1-esterase inhibitor deficiency) can also have attacks of recurrent abdominal painAbdominal pain can be one of the symptoms associated with transient disorders or serious disease. Making a definitive diagnosis of the cause of a person's abdominal pain can be quite difficult, because so many diseases can result in this symptom. Introduc, leading to unnecessary laparotomyA laparotomy is a surgical operation involving an incision through the abdominal wall. It gives access to all abdominal organs, and is the first step in any major diagnostic or therapeutic surgical procedure of these organs. In a diagnostic laparotomy the, and there is an increased incidence of autoimmune disease (e.g. lupus erythematosus, glomerulonephritis and hypothyroidism) due to altered activity of the complement system.



Read more »

Non User