Index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Home > Acute phase protein
Acute phase proteins are a class of proteins that are synthetized in the liver in response to inflammation. This response is called the acute phase reaction.In response to injury, local inflammatory cells ( neutrophil granulocytes and macrophages) secrete a number of cytokines into the bloodstream, most notably IL-1, IL-6, IL-11 and TNF-alpha.
The liver responds by producing a large number of acute phase reactants, most notably:
- C-reactive protein
- Alpha 1-antitrypsin
- Alpha 1-antichemotrypsin
- Alpha 2-macroglobulin
- some coagulation factors ( Fibrinogen, prothrombin, factor VIIIFactor VIII (FVIII) is an essential clotting factor. The lack of normal FVIII causes Hemophilia A, an inherited bleeding disorder. Genetics The gene for Factor VIII is located on the X chromosome (Xq28). Physiology FVIII is a glycoprotein synthesized and, plasminogen)
- ComplementThe complement system is a complex biochemical cascade of the immune system, leading to cytolysis, chemotaxis, opsonization and inflammation, it can mark pathogens for phagocytosis. It consists of more than 35 proteins. 12 which are directly involved in t factors
- Serum amyloid protein (see amyloidAmyloid describes various types of protein aggregations that share specific traits when examined microscopically. The name amyloid comes from the early mistaken identification of the substance as starch based on crude iodine-staining techniques amylum in)
Proteins Immune systemThe immune system is any system present in an organism to prevent predation by biological agents. All living organisms have these protective measures, although they vary radically in scope and mechanism. In humans and domesticated animals, the immune syst
Read more »